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New Research: Acupuncture Before IVF for Poor Ovarian Response (2026)

A 2026 multicenter trial tested acupuncture before IVF in women with poor ovarian response. Here's what it found — and what it did not prove.

By Seven MedicinePublished October 12, 20262 min read

A new randomized trial published in February 2026 looked at acupuncture for women with poor ovarian response — when the ovaries produce fewer eggs than expected during IVF stimulation. Because claims about acupuncture and IVF are common online, we want to explain exactly what this study did and didn't show.

What the study looked at

Researchers at nine hospitals in China randomly assigned 140 women (aged 40 or younger) with poor ovarian response to either 36 acupuncture sessions before IVF stimulation, or IVF alone. Their main question was whether acupuncture increased the number of eggs retrieved.

What it found

  • Eggs retrieved (the main outcome): no significant difference — a median of two in both groups.
  • Total clinical pregnancy: 34% with acupuncture vs 21% without — not statistically significant.
  • Total live birth: 21% vs 16% — not statistically significant.
  • Some intermediate measures differed: the embryo cleavage rate was higher and a baseline hormone level (FSH) was lower in the acupuncture group.

What it did NOT prove

This study does not show that acupuncture improves IVF success. The outcomes patients care about most — pregnancy and live birth — were not significantly different. Intermediate lab markers don't automatically translate into more babies.

Important limitations

  • There was no sham (placebo) acupuncture group, so the effects of extra attention and care can't be separated from needling itself.
  • The study was small and not designed to detect differences in live birth.
  • A published commentary raised these same concerns, along with variation in how many sessions women actually received before stimulation.

How it fits with other research

The largest sham-controlled IVF trial (848 women) found no difference in live births between acupuncture and sham. A 2026 review of small trials in diminished ovarian reserve reported more pregnancies with acupuncture, but rated its certainty very low to moderate — and its results conflict with this larger multicenter trial. A new placebo-controlled trial has been announced, but it is only a protocol so far: a plan, not evidence.

What this may mean for you

If you're considering acupuncture during IVF, it's reasonable to see it as supportive care — for stress, sleep and feeling cared for during a demanding process — rather than as a way to raise your chances of a live birth.

Questions to discuss with your fertility team

  • Is there anything in my protocol that acupuncture timing should work around?
  • Are there any reasons I shouldn't have acupuncture during stimulation or around transfer?
  • What would you consider the most evidence-based ways to support my cycle?

How Seven Medicine uses acupuncture

Dr. Kristina offers acupuncture as supportive care alongside your fertility clinic — never in place of it — times visits around your clinic's calendar, and never changes your medical protocol.

References

  1. [1]Su C, Wang X, Liu X, et al. Effect of acupuncture for poor ovarian response: a multicenter randomized controlled trial. Front Endocrinol. 2026;17:1765527. PubMed 41837144 (opens in a new tab) · DOI 10.3389/fendo.2026.1765527 (opens in a new tab)· randomized controlled trial (no sham control)
  2. [2]Wang C, Chen X, Wang C, Wu R. Commentary: Effect of acupuncture for poor ovarian response: a multicenter randomized controlled trial. Front Endocrinol. 2026;17. PubMed 42222090 (opens in a new tab) · DOI 10.3389/fendo.2026.1838768 (opens in a new tab)· commentary
  3. [3]Smith CA, de Lacey S, Chapman M, et al. Effect of Acupuncture vs Sham Acupuncture on Live Births Among Women Undergoing In Vitro Fertilization: A Randomized Clinical Trial. JAMA. 2018;319(19):1990-1998. PubMed 29800212 (opens in a new tab) · DOI 10.1001/jama.2018.5336 (opens in a new tab)· randomized controlled trial (sham-controlled)
  4. [4]Xu L, Liang X, et al. Clinical evidence of acupuncture for infertile women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis. Front Endocrinol. 2026;17. PubMed 42358682 (opens in a new tab) · DOI 10.3389/fendo.2026.1840157 (opens in a new tab)· systematic review and meta-analysis
  5. [5]Liu X, Su C, et al. Effect of acupuncture pretreatment on clinical pregnancy rate in women with diminished ovarian reserve undergoing IVF-ET: study protocol for a multicenter randomized controlled trial. Front Endocrinol. 2026;17. PubMed 41727691 (opens in a new tab) · DOI 10.3389/fendo.2026.1723278 (opens in a new tab)· study protocol (no results)

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